Command + Option + F5 summons a complete list of accessibility options, including turning screen magnification on or off, increasing or decreasing contrast, and inverting screen colors. The OS X operating system includes built-in features to assist users with a range of physical and motor disabilities. Getting Help with OS X Accessibility for Users with Visual Impairments
Low Vision and Blind Computer Screen Access Using the VoiceOver Screen Reader Low Vision Computer Screen Access Using the Zoom Screen Magnifier